Larval melanocyte regeneration following laser ablation in zebrafish.
نویسندگان
چکیده
A method to specifically ablate melanocytes in a genetically tractable organism would facilitate the analysis of melanocyte regeneration and regulation. We have demonstrated that a Q-switched neodymium:yttrium-aluminum-garnet dermatology laser kills larval melanocytes in zebrafish. Following melanocyte ablation, new melanocytes regenerate from unpigmented precursors. We show that melanocyte regeneration following laser ablation requires kit receptor tyrosine kinase.
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ورودعنوان ژورنال:
- The Journal of investigative dermatology
دوره 123 5 شماره
صفحات -
تاریخ انتشار 2004